Automated and real-time cell counting, analysis and quality control : save time and reduce risk of contamination
Our analyzers, driven by machine learning, support scientists and biomanufacturers when scaling up their cell culture processes and operations for cell- & gene-based therapeutics and vaccine development & manufacturing.
We provide:
Automation: real-time monitoring of Critical Process Parameters (CPPs) and Critical Quality Attributes (CQAs).
On-line readout: no sampling means no risk of contamination.
Robust measurements: thousands of images are generated covering the entire duration of the culturing process.
Extensive information on CPPs, such as viability, viable cell density (VCD), total cell density (TCD) and CQAs such as cell health and cell phenotype (morphology-related) enables better characterization and control of the cell culture bioprocesses.
Ovizio’s analyzers offer convenient and robust solutions for automated cell counting, analysis and quality control.
Each cell is assigned a fingerprint based on multiple morphological and optical characteristics. This provides precise tracking of cells, along with their status, morphological changes and even differentiation. Our algorithms are already capable of cell counting, assessing viability, detecting beads or cell-morphology changes
such as T cell activation and can be customized upon request.
Increase the throughput of your cell-image analysis.
The qMod has allowed us to investigate marine organisms at high magnification in combination with fluorescence imaging in a simple, easy-to-use manner. In this way we can confirm our observations with the appropriate stains or inherent fluorescence of cells when studying for example, the viability of cells or lipid body content. The ease of use of the instrument and software and support of Ovizio have been most beneficial to our students and us in trying to address key scientific questions.Eva-Maria Zetsche
Dr, Researcher at the Royal Netherlands Institute for the Sea
Ovizio’s iLine S technology has allowed us to evaluate the confluence in our fully closed multiplate bioreactor system. The direct on-site support, technical hands on and efficient follow-up have been key in reaching this milestone. Currently, Promethera is impatiently looking forward to the release of new tools allowing real-time non-invasive monitoring of apoptosis/phenotypic changes of 2D cultures. This would substantially contribute to the in process and quality control of cell therapeutic products in general. Sarah Snykers, Senior R&D/QC manager, Promethera Biosciences
Commercializing a cell therapy requires opening the ‘black box' of traditional cell culture. Ovizio's qMod has unique imaging software that allows for unprecedented quantification of cell parameters, from evaluating a single cell to the population as a whole. Also, the set-up was fast and the interface so easy to use that we now use it daily to evaluate confluency and cell morphology. The staff at Ovizio has happily worked with us to optimize the algorithms and identify the key parameters critical to monitor in our process.Lara Ionescu Silverman, PhD, Senior Manager, R&D Discgenics
Machine Learning
The machine learning (ML) field uses artificial intelligence (AI) algorithms to allow computers to automatically “learn” how to perform a specific task without being explicitly programmed to do so. Ovizio’s services can create custom ML models to suit your specific needs.
