A joint talk with Bristol Myers Squibb presented at the ASGCT digital event held on May 14, 2020.

The aim of this work was to evaluate the iLine F microscope’s on-line, continuous monitoring of T-cell culture and compare the measurements to an offline cell counter (not disclosed) for more than 250 runs. The results of 7 runs are shown below.

Conclusions

After >250 successful bioreactor expansion runs with the iLine F platform

  • iLine F demonstrates good performance within multiple processes.
  • iLine F demonstrates good comparability with reference cell counter.
  • iLine F demonstrated no negative impact to existing processes.