qMod camera

Digital camera

Ovizio’s qMod quantitative phase imaging device is a camera that can convert a regular brightfield microscope into a versatile 3D quantitative imaging platform for biological applications. It can be fixed onto the C-mount where a camera is usually attached to the microscope. The qMod is a convenient and fast solution for direct cell counting in transparent supports, from petri dishes, flasks and multi-well plates to multi-layer vessels.

Designed for high precision, the qMod generates real-time holographic fingerprints of each cell, enabling the user to select and observe cells individually, based on a pre-defined set of parameters. Using the OsOne software, scientists can track changes, distinguish between living and dead cells, and monitor the aggregation rate. To offer the best possible resolution every time, images acquired with the OsOne software can be refocused post acquisition.

Furthermore, when combined with a fluorescence microscope, the qMod can overlay the fluorescent signal with the hologram. This unique approach opens the door to even more applications, with the possibility of confirming results in a dye-free set-up, avoiding sample preparation, reagents and cell fixation, and thereby also eliminating the need to use potentially toxic and often expensive reagents.